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Discovery and Development of the Helicase–Primase Inhibitor Pritelivir for the Treatment of Immunocompromised Patients with Resistant HSV Infection
Alexander Birkmann
Successful treatment and secondary prophylaxis with pritelivir for a recurrent multi-drug resistant HSV-1 infection in an allogeneic hematopoietic stem cell transplant recipient
Bussini Linda, Giardina Federica A.M., Paolucci Stefania, Mannina Daniele, Birkmann Alexander, Bartoletti Michele
Refractory and Resistant Herpes Simplex Virus Mucocutaneous Infections in Immunocompromised Patients: Literature Review and Proposed Definitions for Use in Clinical Trials
Roy F Chemaly, Tali Shafat, Anna Wald, Camille N Kotton, Genovefa Papanicolaou, Michelle K Yong, Veronica Miller, Takashi E Komatsu, Charu Mullick , Aimee C Hodowanec, Gabriel Westman, Fareed Khawaja, Alexander Birkmann, Per Ljungman
Overview on the management of herpes simplex virus infections: Current therapies and future directions
Alexander Birkmann, Rob Saunders
Effect of Renal and Hepatic Impairment on the Pharmacokinetics of Pritelivir and Its Metabolites
Katharina Erb-Zohar, Susanne Bonsmann, Jörg Pausch, Melanie Sumner, Alexander Birkmann, Holger Zimmermann , Atef Halabi, Dirk Kropeit
Pritelivir for The Treatment of Nucleoside Analogue-Resistant Orolabial Herpes Simplex Virus 2 in a Person Living with HIV
Andrew Purssell, Kennedy Leung, Pierre Giguère, Jonathan B Angel
Evaluation Of The Clinical Drug-Drug Interaction Potential Of Pritelivir On Transporters And Cyp450 Enzymes Using A Cocktail Approach
Michiel de Vries, Susanne Bonsmann, Jörg Pausch, Melanie Sumner, Alexander Birkmann, Holger Zimmermann, Dirk Kropeit
Mass Balance and Metabolite Profile After Single and Multiple Oral Doses of Pritelivir in Healthy Subjects
Susanne Bonsmann, David McCormick, Jörg Pausch, Michiel de Vries, Melanie Sumner, Alexander Birkmann, Holger Zimmermann, Dirk Kropeit
A Multi-Center Assessment of The Outcomes and Toxicities of Foscarnet for Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex in Immunocompromised Patients
Sarah P Hammond, Manickam Rangaraju, Melanie Sumner, Burkhard Timmler, Pranatharthi Chandrasekar, Robin K Avery
Efficacy and safety of extended duration letermovir prophylaxis in recipients of haematopoietic stem-cell transplantation at risk of cytomegalovirus infection: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Domenico Russo, Michael Schmitt, Sylvain Pilorge, Matthias Stelljes, Toshiro Kawakita, Valerie L Teal, Barbara Haber, Charlene Bopp, Sanjeet S Dadwal, Cyrus Badshah