• Indications and medical need
  • Urgent need for more effective antiviral drugs

In recent years, the threat of a viral epidemic, or even a pandemic, has become more realistic than ever before. Besides new threats (e.g. SARS or Ebola virus), familiar viral infections are becoming more difficult to treat due to the occurrence of resistant virus strains. It is obvious that there is an urgent need for more effective antiviral drugs from new compound classes, directed not only against what now can be termed the "classical" viral targets, but also against novel targets and thus with novel mechanisms of action.